AxsJAX at Google
An example of this kind of challenge is with gmail. There's a lot going on in gmail that doesn't require going back to the Google mail server. So, the problem is more similar to accessing applications on the desktop than static webpages. But, these applications are on the web, so you can do some clever stuff. Actually, Charles and TV are doing the clever stuff.
If you are interested in new ideas in accessibility, check out the video of this presentation. It was a little like a cooking show: they whip up a fully cooked roast in about an hour, if you follow my analogy. It was very understandable, and has really made me think this week about how AxsJAX ties into my Raising the Floor theme.